Recent advances in clinical and laboratory research have expanded the knowledge of many rare diseases and provided a deeper insight into their pathogenesis, diagnosis, and treatment. As medical doctors are increasingly being called upon to face a wider variety of rare disorders, publications dealing with this issue are particularly welcome. Rare diseases may variably affect the skin and mucous membranes and many of them may be suspected or unequivocally diagnosed by a careful clinical examination. The book by Professor Khang helps to become familiar with skin diseases rarely dealt with in routine daily practice, pointing out the most relevant clinical features helpful to address the most proficient diagnostic workout. The goal of this book is to particularly enhance the expertise of physicians in the pathogenesis, diagnosis, and treatment of rare dermatologic disorders, with special regard to those occurring in non-Western countries. This feature provides added value for those unfamiliar with neglected tropical diseases. The book is well-written and well-illustrated and may represent a valuable resource for those physicians wishing to broaden their knowledge of rare skin diseases. It may be of interest not only to dermatologists, but also to pediatricians, general practitioners, and clinicians of other specialties of medicine, as well as nurses and medical students. The illustrations provided offer a useful review of many representative rare skin diseases and are accompanied by a detailed and instructive text. Professor Khang efforts to share his clinical expertise have produced an enjoyable and informative reading that may not only help to familiarize with the diagnostic clues of different cutaneous rare disorders but also offers paves the way to new future developments in this field. I enjoyed reading this book and I congratulate Professor Khang on this high-quality editorial contribution.